Diabetic Nephropathy

Diabetic Nephropathy

"Diabetic Nephropathy" ed. by John S. D. Chan
InTAvE | 2012 | ISBN: 9535105434 9789535105435 | 175 pages | PDF | 8 MB

Internationally renowned experts have provided data on their own studies, and discuss the relative usefulness of their work in relation to diabetic nephropathy.
The first section describes the novel role of intrarenal renin-angiotensin-aldosterone system (RAAS) and oxidative stress in the development of diabetic nephropathy and discusses the current and novel pharmacological interventions in the treatment of diabetic nephropathy.
The second section discusses other important contributors outside of the RAAS in the pathogenesis of diabetic nephropathy including AGE/RAGE, epithelial-mesenchymal-transition (EMT) and immune cytokines.
Features: Provides novel information on various pathophysiological determinants in the development of diabetic nephropathy Provides novel information on various pharmacological interventions of diabetic nephropathy

Section 1. Systemic and Local Intrarenal Renin-Angiotensin-Aldosterone System in the Development of Diabetic Nephropathy
1 Up-Regulation of Renin-Angiotensin System in Diabetes and Hypertension: Implications on the Development of Diabetic Nephropathy
2 Renal Angiotensinogen Gene Expression and Tubular Atrophy in Diabetic Nephropathy
3 Diabetic Nephropathy: Role of Aldosterone and Benefits of Therapy with Aldosterone Receptor Blocker
4 Drug and Diabetic Nephropathy
Section 2. Novel Therapeutic Molecules in Diabetic Nephropathy
5 Kidney ADP-Ribosyl Cyclase Inhibitors as a Therapeutic Tool for Diabetic Nephropathy
6 Significance of Advanced Glycation End- Products (AGE) and the Receptor for AGE (RAGE) in Diabetic Nephropathy
7 The Contribution of Fibronectin ED-A Expression to Myofibroblast Transdifferentiation in Diabetic Renal Fibrosis
8 Immunoinflammation in Diabetic Nephropathy: Molecular Mechanisms and Therapeutic Options
9 Study of Diabetic Hypertensive Nephropathy in the Local Population of Pakistan
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